RSV Immunization
Protecting Your Little One from RSV: What Parents Need to know
RSV Season Is Here! Learn How to Help Keep Your Baby Healthy and Protected.
At Piedmont Pediatrics, keeping your little ones healthy is always our top priority! As we head into RSV season, we want to help families understand how to protect their babies from Respiratory Syncytial Virus (RSV), a common respiratory virus that can cause serious illness in infants and young children.
The good news? There are now effective ways to help protect babies from severe RSV illness, including immunizations that can reduce the risk of RSV-related hospitalization by approximately 80–90%!
What Is RSV, and Why Is It Important?
Respiratory Syncytial Virus (RSV) is a common respiratory virus that typically causes cold-like symptoms. While most children recover without complications, RSV can be especially serious for infants.
In fact, RSV is one of the leading causes of hospitalization among infants in the United States.
RSV can cause breathing difficulties and respiratory illnesses such as bronchiolitis and pneumonia. That's why taking steps to protect your baby before and during RSV season is so important.
How Can You Protect Your Baby from RSV?
There are two recommended approaches to protecting infants against severe RSV illness. Most babies only need one of these options, not both.
1. Maternal RSV Vaccination During Pregnancy
Expectant mothers may receive the RSV vaccine, Abrysvo, between 32 and 36 weeks of pregnancy during the recommended seasonal window.
When given at least 14 days before delivery, the vaccine allows protective antibodies to pass from mother to baby, helping protect the infant during those important first months of life.
This protection generally lasts for approximately six months after birth.
2. RSV Antibody Immunization for Infants
Babies may also receive a preventive RSV antibody immunization, such as Beyfortus (nirsevimab) or Enflonsia (clesrovimab).
These immunizations provide antibodies directly to the baby, offering protection against severe RSV illness.
RSV antibody immunization is generally recommended for eligible infants during their first RSV season, ideally shortly before the season begins or before leaving the hospital after birth.
Your pediatrician can help determine which option is most appropriate based on your baby's age, health history, and whether you received the maternal RSV vaccine during pregnancy.
Are RSV Immunizations Safe?
RSV immunizations have been studied for safety and effectiveness. Most reported side effects are mild and short-lived.
Possible side effects of the maternal RSV vaccine include:
- Soreness at the injection site
- Headache
- Muscle or joint aches
- Nausea or fatigue
Possible side effects of infant RSV antibody immunizations include:
- Mild redness, swelling, or discomfort at the injection site
- Rash
Serious reactions are rare. If you have questions or concerns, our pediatric team is always happy to help you understand the benefits and potential risks.
When Should My Baby Receive RSV Protection?
Timing matters when it comes to RSV prevention!
In most areas of the United States, RSV season typically runs from fall through early spring.
Protecting your baby before or early in RSV season helps ensure they have antibodies when they are most likely to be exposed.
Every family's situation is different, so we encourage you to speak with your pediatrician about the best timing and options for your little one.
We're Here to Help Protect Your Family!
At Piedmont Pediatrics, we understand that keeping your baby healthy comes with lots of questions, especially during cold and flu season.
Our team is here to provide trusted guidance, answer your questions, and help you make informed decisions about your child's health.
Have questions about RSV or whether your baby should receive an RSV immunization?
Call our office at 540-347-9900 to speak with our team about RSV prevention and immunization options.
Together, we can help give your little one a healthier start!
For additional information about RSV prevention, visit the American Academy of Pediatrics or the Centers for Disease Control and Prevention.
This article is intended for educational purposes and does not replace individualized medical advice from your child's healthcare provider.

